上級研究員 鄭 誠虎
学歴
| 1994年 | 京都大学理学部卒業（主に化学を修める） |
| 1996年 | 京都大学大学院理学研究科化学専攻修士課程修了 |
| 1999年 | 京都大学大学院理学研究科化学専攻博士課程修了（博士（理学）） |
研究歴
| 1999年 | ミュンヘン工科大学 博士研究員 |
| 2002年 | ローマ大学 博士研究員 |
| 2003年 | モンペリエ第二大学 博士研究員 |
| 2004年 | 分子科学研究所 助教 |
| 2010年 | ソウル大学 研究教授 |
| 2011年 | 淑明女子大学 研究教授／責任研究員 |
| 2021年 | 理化学研究所生命機能科学研究センター 上級研究員 |
受賞歴
| 2009年 | 日本物理学会若手奨励賞（領域12・化学物理） |
所属学会
韓国化学会
研究テーマ
- 統計力学（主に液体論）をベースにした手法の開発と生体高分子系への応用
出版物
- Time-dependent communication between multiple amino acids during protein folding.
S.-H. Chong and S. Ham
Chemical Science, 12, 5944–5951 (2021) - Local environment effects on charged mutations for developing aggregation-resistant monoclonal antibodies.
J. Lee, S.-H. Chong and S. Ham
Scientific Reports, 10, 21191 (13 pages) (2020) - Explicit characterization of the free energy landscape of pKID–KIX coupled folding and binding.
S.-H. Chong, H. Im and S. Ham
ACS Central Science, 5, 1342–1351 (2019) - Folding free energy landscape of ordered and intrinsically disordered proteins.
S.-H. Chong and S. Ham
Scientific Reports, 9, 14927 (9 pages) (2019) - A new computational method for protein–ligand binding thermodynamics.
S.-H. Chong and S. Ham
Bulletin of Korean Chemical Society, 40, 180–185 (2019) - Examining a thermodynamic order parameter of protein folding.
S.-H. Chong and S. Ham
Scientific Reports, 8, 7148 (9 pages) (2018) - Role of electrostatic interactions in determining the G-quadruplex structures.
J. Lee, H. Im, S.-H. Chong and S. Ham
Chemical Physics Letters, 693, 216–221 (2018) - Dynamics of hydration water plays a key role in determining the binding thermodynamics of protein complexes.
S.-H. Chong and S. Ham
Scientific Reports , 7, 8744 (10 pages) (2017) - Computer simulations of intrinsically disordered proteins.
S.-H. Chong, P. Chatterjee, and S. Ham
Annual Review of Physical Chemistry, 68, 117–134 (2017) - Anomalous dynamics of water confined in protein–protein and protein–DNA interfaces.
S.-H. Chong and S. Ham
Journal of Physical Chemistry Letters, 7, 3967–3972 (2016) - New computational approach for external entropy in protein–protein binding.
S.-H. Chong and S. Ham
Journal of Chemical Theory and Computation, 12, 2509–2516 (2016) - Dissecting protein configurational entropy into conformational and vibrational contributions.
S.-H. Chong and S. Ham
Journal of Physical Chemistry B , 119, 12623–12631 (2015) - Structural and thermodynamic characteristics of amyloidogenic intermediates of -2-microglobulin.
S.-H. Chong, J. Hong, S. Lim, S. Cho, J. Lee, and S. Ham
Scientific Reports, 5, 13631 (9 pages) (2015) - Structural versus energetic approaches for protein conformational entropy.
S.-H. Chong and S. Ham
Chemical Physics Letters, 627, 90–95 (2015) - Distinct role of hydration water in protein misfolding and aggregation revealed by fluctuating thermodynamics analysis.
S.-H. Chong and S. Ham
Accounts of Chemical Research, 48, 956–965 (2015) - Thermodynamic-ensemble independence of solvation free energy.
S.-H. Chong and S. Ham
Journal of Chemical Theory and Computation, 11, 378–380 (2015) - Site-directed analysis on protein hydrophobicity.
S.-H. Chong and S. Ham
Journal of Computational Chemistry, 35, 1364–1370 (2014) - Protein folding thermodynamics: A new computational approach.
S.-H. Chong and S. Ham
Journal of Physical Chemistry B, 118, 5017–5025 (2014) - Interaction with the surrounding water plays a key role in determining the aggregation propensity of proteins.
S.-H. Chong and S. Ham
Angewandte Chemie International Edition, 53, 3961–3964 (2014) - Assessing the influence of solvation models on structural characteristics of intrinsically disordered protein.
S.-H. Chong and S. Ham
Computational and Theoretical Chemistry, 1017, 194–199 (2013) - Conformational entropy of intrinsically disordered protein.
S.-H. Chong and S. Ham
Journal of Physical Chemistry B, 117, 5503–5509 (2013) - Structural heterogeneity in familial Alzheimer’s disease mutants of amyloid-beta peptides.
S.-H. Chong, J. Yim, and S. Ham
Molecular BioSystems, 9, 997–1003 (2013) - Aqueous interaction site integral-equation theory that exactly takes into account intramolecular correlations.
S.-H. Chong and S. Ham
Journal of Chemical Physics, 137, 154101 (17 pages) (2012) - Elucidating the molecular origin of hydrolysis energy of pyrophosphate in water.
J. Hong, N. Yoshida, S.-H. Chong, C. Lee, S. Ham, and F. Hirata
Journal of Chemical Theory and Computation, 8, 2239–2246 (2012) - Impact of chemical heterogeneity on protein self-assembly in water.
S.-H. Chong and S. Ham
Proceedings of the National Academy of Sciences U.S.A., 109, 7636–7641 (2012) - Component analysis of the protein hydration entropy.
S.-H. Chong and S. Ham
Chemical Physics Letters, 535, 152–156 (2012) - Atomic-level investigations on the amyloid- dimerization process and its driving forces in water.
S.-H. Chong and S. Ham
Physical Chemistry and Chemical Physics, 14, 1573–1575 (2012) - Structural and thermodynamic characteristics that seed aggregation of amyloid-beta protein in water.
S.-H. Chong, M. Park, and S. Ham
Journal of Chemical Theory and Computation, 8, 724–734 (2012) - Atomic decomposition of the protein solvation free energy and its application to amyloid-beta protein in water.
S.-H. Chong and S. Ham
Journal of Chemical Physics, 135, 034506 (8 pages) (2011) - Structural and thermodynamic investigations on the aggregation and folding of acylphosphatase by molecular dynamics simulations and solvation free energy analysis.
S.-H. Chong, C. Lee, G. Kang, M. Park, and S. Ham
Journal of the American Chemical Society, 133, 7075–7083 (2011) - Zwanzig-Mori equation for the time-dependent pair distribution function.
S.-H. Chong, C.-Y. Son, and S. Lee
Physical Review E, 83, 041201 (10 pages) (2011) - Propagator for diffusive dynamics of an interacting molecular pair.
S. Lee, C. Y. Son, J. Sung, and S.-H. Chong
Journal of Chemical Physics, 134, 121102 (4 pages) (2011) - Configurational entropy of protein: A combined approach based on molecular simulation and integral-equation theory of liquids.
S.-H. Chong and S. Ham
Chemical Physics Letters, 504, 225–229 (2011)